SPINA (Structure Parameter Inference Approach) is a method for calculating constant structure parameters of endocrine feedback control systems from hormone levels obtained in vivo.
With a first pilot application having been introduced for evaluating of thyrotropic axis, additional applications of this innovative method are in status of development. SPINA Carb, an approach for assessment of beta-cell function, e. g. in patients with diabetes mellitus, impaired glucose tolerance or unexplained hypoglycemia, has been formulated and is currently being evaluated.
Please find current background
information on this approach at the site of the